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Sampson L. Abu

Sampson L. Abu, OD.

Sampson L. Abu, O.D., FAAO, Dip. ABO

Medical Optometrist & Clinical Glaucoma Researcher

Expertise in glaucoma progression, ocular surface inflammation, and advanced diagnostic analytics.

Optometry measurement device

About Dr. Abu

Dr. Sampson L. Abu is a board-certified medical optometrist and researcher based in Athens, Georgia. He specializes in the diagnosis and management of ocular disease, including glaucoma, dry eye disease, neuro-ophthalmic conditions, and vascular disease eye complications.

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At Thomas Eye Center, Dr. Abu integrates advanced imaging, functional testing, and evidence-based clinical decision-making to manage complex ocular disease. His clinical work is informed by rigorous scientific training and a patient-centered, data-driven approach.

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Dr. Abu completed an NIH-funded postdoctoral fellowship at the University of Alabama at Birmingham, where his research focused on early detection of glaucoma progression and treatment adherence, and utilizing computational modeling of structure–function data. His work has been published in Ophthalmology, Translational Vision Science & Technology, Scientific Reports, J Glaucoma, and other leading journals.

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He completed an Ocular Disease Residency at Omni Eye Services in Atlanta, is a Fellow of the American Academy of Optometry and a diplomate of the American Board of Optometry. Dr. Abu has presented his research at major national and international scientific meetings, including the American Academy of Optometry, ARVO, the World Glaucoma Congress, and the North American Perimetric Society.

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He brings a clear, evidence-driven perspective to ocular disease management and the evaluation of emerging eyecare technologies.

Patient's eye

Clinical Focus Areas

  • Glaucoma diagnosis, staging, and progression monitoring

  • Optical coherence tomography (OCT) data interpretation

  • Visual field testing and interpretation

  • Dry eye disease

  • Neuro-ophthalmic conditions

  • Diabetes-related and other systemic ocular manifestations

Approach:

Evidence-based. Data-informed. Patient-centered.

Research & Scientific Work

Dr. Abu’s research focuses on advancing early detection and monitoring of glaucoma progression. through structure–function modeling, diagnostic analytics, and individualized progression assessment. His work harnesses statistical modelling to integrate OCT-derived retinal nerve fiber layer (RNFL) and visual field metrics to improve the sensitivity and clinical utility of glaucoma diagnostic tests.

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In addition to his glaucoma research, Dr. Abu has contributed to studies in ocular surface disease, immunology, diabetes-related ocular physiology, and global eyecare practices. His publications span leading journals and reflect a breadth of inquiry across both clinical and translational eyecare research.

Research Interests:

  • Glaucoma progression modeling with Structure–function (OCT + visual field) integration

  • Retinal biomarkers for neurodegeneration

  • Medication adherence in glaucoma

  • Ocular surface and inflammatory disease mechanisms

Featured Peer-Reviewed Publications:

Journal: Translational Vision Science & Technology (2025)
Summary: Introduces a sector-based probability model to improve detection of localized RNFL progression, enhancing the diagnostic precision of OCT imaging.
Journal: Current Opinion in Allergy and Clinical Immunology (2024)
Summary: Reviews emerging receptor-targeted therapies for allergic conjunctivitis, highlighting new pharmacologic mechanisms with clinical relevance.
Journal: Translational Vision Science & Technology (2022)
Summary: Demonstrates enhanced sensitivity in detecting glaucoma progression through postprocessed visual field algorithms.
Journal: Ophthalmology (2022)
Summary: Evaluates real-world adherence patterns among glaucoma patients during the COVID-19 pandemic and identifies factors influencing disease stability.

Journal: Journal of Glaucoma (2021)

Summary: Examines progression patterns across glaucoma subtypes and identifies variations in structural and functional indicators.

Journal: PLOS ONE (2020)

Summary: Introduces a unified structure–function model combining OCT and visual field data for earlier and more accurate detection of glaucomatous change.

Journal: Scientific Reports (2020)

Summary: Validates a structure–function model across diverse clinical presentations, demonstrating robustness for real-world glaucoma monitoring.

Selected Scientific Presentations:

Evaluating Focal RNFL Thinning in Monitoring Glaucoma Progression

Conference: American Academy of Optometry (2023)

Summary: Analyzes sectoral RNFL thinning to refine early detection of glaucomatous progression.

Sensitivity of Postprocessed Visual Field Data to Identify Rapid Progression

Conference: American Academy of Optometry (2021)

Summary: Simulation study assessing improved detection of rapid visual field deterioration using postprocessed data.

Mutual Information Analysis of Inter-Eye Visual Field Progression

Conference: American Academy of Optometry / World Congress of Optometry (2019)

Summary: Uses mutual information to understand how visual field deterioration in one eye relates to the fellow eye.

Predicting Glaucoma Progression in One Eye Based on the Fellow Eye

Conference: ARVO Annual Meeting (2019)

Summary: Investigates inter-eye relationships to support predictive modeling for future glaucoma progression.

Early Detection of Glaucoma Progression Using Individual and Combined Indices

Conference: Southeastern Vision Conference / ARVO Abstract (2018)

Summary: Compares structural and functional metrics to enhance early glaucoma progression detection.

Macro photo of colored purple human eye texture background extreme blue eye macro shot Ton

Consulting & Advisory Engagements

Dr. Abu partners with organizations working in glaucoma, ocular surface disease, diagnostic imaging, and data-driven innovation. His background in clinical disease management, NIH-funded research, and advanced imaging analytics allows him to contribute meaningful insight to teams seeking clinician-informed perspectives on technology, diagnostics, and therapeutic development.
 

He welcomes opportunities to support projects that benefit from thoughtful clinical interpretation, evidence-based analysis, and a practical understanding of real-world patient care.

Areas of Collaboration:

  • Interpretation of OCT and visual field analytics for diagnostic refinement

  • Clinical insight on glaucoma progression patterns and monitoring strategies

  • Evaluation of emerging diagnostic technologies and early detection tools

  • Input on study design, clinical endpoints, and methodological considerations

  • Review of scientific or educational materials for accuracy and clarity

  • Perspective on medication adherence and real-world treatment dynamics

Contact

For professional inquiries or potential engagements, please use the form below.
Dr. Abu welcomes communication from organizations and teams working in glaucoma, ocular disease, diagnostics, imaging, and clinical research.

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If preferred, you may also reach him at: contact@sampsonabuod.com.

Thank you for your message. Your inquiry has been received and will be reviewed. You will be contacted if the request aligns with current collaboration areas.

© 2026 by Sampson L. Abu. All rights reserved.

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